Amla scored his 20th Test hundred (118*) as South Africa reached 245 for 8 at stumps on the opening day of the first Test, which was dominated by the Pakistan bowlers.
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South African skipper Graeme Smith has won the toss and elected to bat first with JP Duminy returning back to the Test team.
On the other hand Shan Masood and Zulfiqar Babar are playing their first match for Pakistan. Abdur Rehman misses out with a sore back.
Pakistan: Shan Masood, Khurram Manzoor, Azhar Ali, Younis Khan, Misbah-ul-Haq(c), Asad Shafiq, Adnan Akmal(w), Saeed Ajmal, Zulfiqar Babar, Junaid Khan, Mohammad Irfan
South Africa: Graeme Smith(c), Alviro Petersen, Hashim Amla, Jacques Kallis, AB de Villiers(w), Jean-Paul Duminy, Faf du Plessis, Robin Peterson, Vernon Philander, Dale Steyn, Morne Morkel