Washington: Scientists have for the first time built a detailed molecular model of the complex structure of the inner protein shell of HIV, paving way for potential new treatments for the deadly virus.
A team led by researchers at the University of Pittsburgh School of Medicine described the 4-million-atom structure of the HIV's capsid, or protein shell. The findings, published in the journal Nature, could lead to new ways of fending off an often-changing virus that has been very hard to conquer.
Scientists have long struggled to decipher how the HIV capsid shell is chemically put together, said senior author Peijun Zhang, associate professor at the University of Pittsburgh School of Medicine.
"The capsid is critically important for HIV replication, so knowing its structure in detail could lead us to new drugs that can treat or prevent the infection," she said....
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12:49 PM, May 31, 2013
The Defence Acquisition Council is expected to approve changes to procurement rules on Tuesday and sources said the new rules will give domestic industry, both public and private, the right of "first refusal" before the import option is exercised. ...
01:48 PM, Apr 02, 2013
Chandigarh: Punjab is headed for a record wheat procurement of 140 lakh tonnes this season, officials of the state food and supplies department said in Chandigarh on Tuesday. "Punjab is all set for achieving a new record in wheat procurement as the state government would begin the biggest ever procurement operations in the state from April 1, 2013," a spokesman of the department said. According to state agriculture department, 161.59...
03:45 AM, Mar 27, 2013
New Delhi: After the AgustaWestland scandal, the Defence Ministry is planning to tweak its procurement procedures. But insiders claim these changes are unnecessary and misplaced and reflect a knee jerk reaction from the government. South Block is abuzz with reports of an imminent change in the defence procurement procedures. The changes will apparently favour domestic industry and give them the right of first refusal when it comes to building weapons...
10:28 AM, Mar 26, 2013
New Delhi: Defence Ministry's move to have 'life cycle cost' clause in tenders for military hardware, including in one for the 126 Multi-Role Medium Combat Aircraft (MMRCA), has come in for questioning from BJP which fears this could be misused for corruption. BJP leader and former Finance Minister Yashwant Sinha has written to Defence Minister A K Antony, raising a number of questions over the "conceptual shift" in the defence...
05:33 PM, Mar 24, 2013
President Barack Obama continues to believe that going to Iraq was not a wise decision, although he agrees Iraq is a better place today as a result of sacrifice made by the US military, 10 years after it invaded the nation in search of chemical and biological weapons. Obama had opposed the Iraq war and ran for presidency on a promise to end it. The last batch American troops left...
07:42 AM, Mar 20, 2013
Dhoni, has been signed as the brand ambassador of Emcure Pharmaceuticals, a company that specialises in tablets, capsules, injectables and Onco products. ...
11:48 PM, Mar 12, 2013
A baby girl in Mississippi who was born with HIV has been cured after very early treatment with standard HIV drugs, US researchers reported on Sunday, in a potentially ground-breaking case that could offer insights on how to eradicate HIV infection in its youngest victims. The child's story is the first account of an infant achieving a so-called functional cure, a rare event in which a person achieves remission without...
08:52 AM, Mar 04, 2013
The 44-year-old actress has been attaching a sliver of snakeskin to her toenails and painting over it with a clear sealant, reported Showbiz spy. ...
12:42 PM, Feb 27, 2013
Three separate studies suggest that regular aspirin use may be linked to prevention of lung cancer, liver cancer and colorectal cancer. ...
01:23 PM, Feb 11, 2013
The armed forces may have to trim some of their ambitious weapons procurement plans after indications that the defence budget could be cut by around four to five per cent if not more, as part of Finance Minister P Chidambaram's plans to lower the deficit. ...
11:31 AM, Feb 01, 2013
Researchers have developed a new software that makes the technology of opening car and home doors using smartphone apps more secure and versatile. ...
12:56 PM, Jan 05, 2013
Toronto: A drug intended for diabetes appears to restore memory in brain cells affected by Alzheimer's disease, researchers say. Medical researchers at the University of Alberta led by Jack Jhamandas took brain tissue from animal models with Alzheimer's disease and tested the tissue in the lab, looking specifically at the cells' memory capacity. When brain cells are shocked by a barrage of electrical impulses, the cells "remember" the experience, which...
06:16 PM, Dec 12, 2012
New Delhi: Even as his Ministry is preparing itself for curtailment of funds, Defence Minister AK Antony on Saturday said there will be no cut in budget for procuring equipment essential for operational preparedness of armed forces. "Everything depends on the entire financial situation of the government...for ammunition and platforms essential for operational preparedness of the armed forces, there would not be any cut," he told reporters on the sidelines...
02:48 AM, Nov 11, 2012
Copenhagen: Chloroquine, an efficacious old drug, is once again beginning to work against malaria, one of the most widespread scourges in the world. Scientists and doctors fear that the malaria parasite will develop resistance to the current frontline treatment against malaria: Artemisinin-based Combination Therapies (ACTs). Resistance (to drugs) monitoring at the University of Copenhagen shows that in several African countries, malaria parasites are succumbing to chloroquine, the American Journal of...
05:18 PM, Oct 03, 2012
Wellington: Vitamin D does not reduce the severity of colds, even for those who received a monthly dose of 100,000 units in a trial, says a study. The association of Vitamin D deficit and susceptibility to viral respiratory tract infections has been unclear, said the University of Otago study. David R. Murdoch, University of Otago, New Zealand, and colleagues conducted a randomized trial to examine the effect of Vitamin D...
10:34 AM, Oct 03, 2012
New Delhi: Pay more for your daily does of calcium now. Milk has become dearer by Rs 2 in the national capital. This is the first hike of the year. A litre of full-cream Mother Dairy milk will now cost Rs 39. Toned milk will cost Rs 31. Mother Dairy has attributed the price hike to a rise in power tariffs, diesel costs and rising milk procurement prices. ...
11:53 AM, Sep 08, 2012
New Delhi: The CBI on Friday questioned suspended BEML Chairman and Managing Director VRS Natarajan in connection with alleged irregularities in procurement and supply of Tatra all-terrain trucks to the Army. CBI sources said Natarajan was grilled at the CBI headquarters in New Delhi for about five hours about issues that have surfaced during raids conducted by the agency at BEML facilities. The probe agency is trying to ascertain the...
11:23 PM, Aug 24, 2012
New Delhi: An internal audit of the Army has raised questions about the supply chain of management of Army's rations. According to its report, the Army is allegedly over-procuring rations for at least two lakh non-existent soldiers. The Indian Army personnel have the option of drawing ration either in cash called the Ration Money Allowance or get cooked meals. Especially when officers and jawans go on leave or are unwell,...
08:09 AM, Aug 20, 2012
London: In a breakthrough expected to develop a 'real cure' for cancer, scientists claimed to have identified cells that cause tumours to grow and are resistant to chemotherapy and radiotherapy causing cancer to relapse. Researchers from Cancer Research UK and University of Texas in separate studies found that the growth and life of a tumour is dependent on one small group of cells, known as cancer stem cells, the Daily...
12:43 PM, Aug 02, 2012
