Chelsea routed Nordsjaelland 6-1 to finish third in Group E, but were unable to qualify to the knockout stage as Juventus defeated Shakhtar Donetsk 1-0 in the Champions League.
CFR Cluj beat Manchester United 1-0 thanks to Luis Alberto's fabulous second-half strike but were denied a spot in the last 16 of the Champions League.
Lionel Messi was carried off on a stretcher with an apparent knee injury as Barcelona were held to 0-0 by Benfica at Camp Nou.
Juventus advanced to the knockout stage of the Champions League by winning 1-0 at Shakhtar Donetsk clinching top spot in Group E.
Bayern Munich beat BATE Borisov 4-1 to make sure of winning Group F and being seeded in the knockout stage of the Champions League.
Kris Commons smashed home a controversial late penalty to earn Celtic a 2-1 victory over Spartak Moscow, booking his team a place in the knockout stage.
Julian Scheiber scored in the second half for Borussia Dortmund to beat Manchester City 1-0 and knock them out of the Champions League.
Cristiano Ronaldo opened the scoring as Real Madrid eased to a 4-1 home victory over Ajax in the Champions League.
Substitute Costas Mitroglou fired Olympiakos to a 2-1 victory over Arsenal in the Champions League.
Zenit St. Petersburg beat AC Milan 1-0 in the Champions League to qualify for the Europa League.