Fernando Torres scored twice as Chelsea returned to winning ways, defeating Sunderland 3-1 in the EPL clash.
Midfielder Mesut Ozil scored two brilliant goals to give Real Madrid a 3-2 win at Valladolid, in the La Liga.
Norwich extended their unbeaten run to nine Premier League matches on Saturday by winning 4-3 at Swansea.
Mikel Arteta scored two goals on penalties, as Arsenal defeated West Brom 2-0, their first win in last four matches.
James McCarthy scored twice as Wigan held QPR to a 2-2 draw on Saturday, extending QPR's winless run to a Premier League record of 16 games.
Aston Villa dropped one place to 16th in the Premier League despite drawing 0-0 with Stoke on Saturday.
Roma captain Francesco Totti scored twice and set up two more goals in a 4-2 win over Fiorentina in the Serie A encounter on Saturday.
Lionel Messi broke Gerd Mueller's 40-year-old record for most goals in a year by scoring for the 86th time in 2012. He scored twice as Barcelona beat Real Betis 2-0 in the Spanish league match.
Robin van Persie scored a stoppage-time winner to give Manchester United a 3-2 win over rivals Manchester City, ending City's unbeaten start to the Premier League season.
Radamel Falcao scored five times to reach 16 goals for the Spanish league, as Atletico Madrid thrashed last-place Deportivo La Coruna 6-0.
Steven Gerard scored an own goal as Liverpool came from behind to beat West Ham 3-2 in the EPL clash.